6TR5
Melatonin-Notum complex
Summary for 6TR5
| Entry DOI | 10.2210/pdb6tr5/pdb |
| Descriptor | Palmitoleoyl-protein carboxylesterase NOTUM, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, DIMETHYL SULFOXIDE, ... (6 entities in total) |
| Functional Keywords | wnt notum inhibitor melatonin, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 45099.55 |
| Authors | Zhao, Y.,Jones, E.Y. (deposition date: 2019-12-17, release date: 2020-01-15, Last modification date: 2024-01-24) |
| Primary citation | Zhao, Y.,Ren, J.,Hillier, J.,Jones, M.,Lu, W.,Jones, E.Y. Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum. J. Pineal Res., 68:e12630-e12630, 2020 Cited by PubMed: 31876313DOI: 10.1111/jpi.12630 PDB entries with the same primary citation |
| Experimental method |
Structure validation
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