6TQB

X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE1 SL RNA motif

6TQB の概要

• エントリーDOI: 10.2210/pdb6tqb/pdb
• 分子名称: Roquin-1, RNA (5'-R(P*GP*GP*AP*AP*AP*UP*UP*AP*UP*AP*UP*UP*AP*AP*UP*UP*UP*CP*C)-3'), 1,2-ETHANEDIOL, ... (7 entities in total)
• 機能のキーワード: roquin, roq domain, rna binding, ucp1, rna binding protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27051.74

構造登録者

Binas, O.,Tants, J.-N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A. (登録日: 2019-12-16, 公開日: 2020-05-27, 最終更新日: 2024-01-24)

• 主引用文献: Binas, O.,Tants, J.N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A.; Structural basis for the recognition of transiently structured AU-rich elements by Roquin.; Nucleic Acids Res., 48:7385-7403, 2020; PubMed: 32491174; DOI: 10.1093/nar/gkaa465

実験手法

X-RAY DIFFRACTION (1.6 Å)