6TN8

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound BI-9564

6TN8 の概要

• エントリーDOI: 10.2210/pdb6tn8/pdb
• 分子名称: Activin receptor type I, 1,4-DIETHYLENE DIOXIDE, 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one, ... (6 entities in total)
• 機能のキーワード: kinase, bmp, inhibitor, signalling, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35621.80

構造登録者

Williams, E.P.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (登録日: 2019-12-06, 公開日: 2019-12-18, 最終更新日: 2024-01-24)

• 主引用文献: Williams, E.P.,Chen, Z.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound BI-9564; To Be Published,

実験手法

X-RAY DIFFRACTION (1.63 Å)