6TM7
Human 14-3-3 sigma isoform in complex with PLP
Summary for 6TM7
Entry DOI | 10.2210/pdb6tm7/pdb |
Related | 6TLF 6TLG |
Descriptor | 14-3-3 protein sigma, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total) |
Functional Keywords | human protein, h14-3-3sigma, signaling protein, complex, pyridoxal phosphate, plp |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 62808.66 |
Authors | Tassone, G.,Pozzi, C.,Mangani, S. (deposition date: 2019-12-03, release date: 2020-03-18, Last modification date: 2024-01-24) |
Primary citation | Iralde-Lorente, L.,Tassone, G.,Clementi, L.,Franci, L.,Munier, C.C.,Cau, Y.,Mori, M.,Chiariello, M.,Angelucci, A.,Perry, M.W.D.,Pozzi, C.,Mangani, S.,Botta, M. Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15:1026-1035, 2020 Cited by PubMed: 32142251DOI: 10.1021/acschembio.0c00039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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