6TLK

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in an open conformation containing NADP+ and methylene-H4MPT

6TLK の概要

• エントリーDOI: 10.2210/pdb6tlk/pdb
• 分子名称: Bifunctional protein MdtA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FORMIC ACID, ... (8 entities in total)
• 機能のキーワード: one-carbon metabolism; enzyme catalysis; dehydrogenase; conformational changes; methylotrophy, oxidoreductase
• 由来する生物種: Methylorubrum extorquens AM1
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 196324.87

構造登録者

Wagner, T.,Huang, G.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S. (登録日: 2019-12-02, 公開日: 2020-02-26, 最終更新日: 2024-01-24)

• 主引用文献: Huang, G.,Wagner, T.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S.; The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase.; J.Mol.Biol., 432:2042-2054, 2020; PubMed: 32061937; DOI: 10.1016/j.jmb.2020.01.042

実験手法

X-RAY DIFFRACTION (1.8 Å)