6TLK

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in an open conformation containing NADP+ and methylene-H4MPT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Bifunctional protein MdtA	polymer	303	31512.7	6	UniProt (P55818) Pfam (PF09176)	Methylorubrum extorquens AM1
2	BA, G, K, M, R... (F, A, B, C, D...)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	6	Chemie (NAP)
3	AA, GA, H, HA, I... (E, F, A, C, D)	FORMIC ACID	non-polymer		46.0	13	Chemie (FMT)
4	J, L (A, B)	5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN	non-polymer		788.7	2	Chemie (H4M)
5	DA, EA, FA, N, O... (F, C, E)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	T (D)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	CA (F)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
8	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	2093	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 288 (UniProt: P55818)

PDB	External Database	Details
Val 289	-	expression tag
Asp 290	-	expression tag
Lys 291	-	expression tag
Leu 292	-	expression tag
Ala 293	-	expression tag
Ala 294	-	expression tag
Ala 295	-	expression tag
Leu 296	-	expression tag
Glu 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	189076.4
Non-Polymers*	Number of molecules	29
	Total formula weight	7248.5
All*	Total formula weight	196324.9

*Water molecules are not included.