6TI1

SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/L-Threonine/Lys230 gem diamine complex

Summary for 6TI1

• Entry DOI: 10.2210/pdb6ti1/pdb
• Descriptor: Serine hydroxymethyltransferase, GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, ... (5 entities in total)
• Functional Keywords: pyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase
• Biological source: Streptococcus thermophilus
• Total number of polymer chains: 2
• Total formula weight: 90939.46

Authors

Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-21, release date: 2020-04-29, Last modification date: 2024-01-24)

• Primary citation: Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I.; Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)