6TDE
Tubulin-inhibitor complex
Summary for 6TDE
Entry DOI | 10.2210/pdb6tde/pdb |
Descriptor | Tubulin alpha chain, Tubulin beta chain, Stathmin-4, ... (9 entities in total) |
Functional Keywords | cytoskeleton, cell division, intracellular transport, cell cycle |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 5 |
Total formula weight | 220791.47 |
Authors | Varela, P.F.,Gigant, B. (deposition date: 2019-11-08, release date: 2020-09-02, Last modification date: 2024-01-24) |
Primary citation | Shchegravina, E.S.,Svirshchevskaya, E.V.,Combes, S.,Allegro, D.,Barbier, P.,Gigant, B.,Varela, P.F.,Gavryushin, A.E.,Kobanova, D.A.,Shchekotikhin, A.E.,Fedorov, A.Y. Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity. Eur.J.Med.Chem., 207:112724-112724, 2020 Cited by PubMed: 32827941DOI: 10.1016/j.ejmech.2020.112724 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.286 Å) |
Structure validation
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