6TD6

Structure of Drosophila melanogaster Dispatched bound to a modified Hedgehog ligand, HhN-C85II

Summary for 6TD6

Entry DOI	10.2210/pdb6td6/pdb
EMDB information	10452 10464
Descriptor	Protein dispatched, Protein hedgehog, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	rnd transporter, dispatched, hedgehog, transmembrane domain, ectodomain, cholesteryl hemisuccinate, detergent micelle, digitonin, monomer, membrane protein
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	2
Total formula weight	192012.61
Authors	Korkhov, V.M.,Cannac, F. (deposition date: 2019-11-07, release date: 2020-06-03, Last modification date: 2020-07-29)
Primary citation	Cannac, F.,Qi, C.,Falschlunger, J.,Hausmann, G.,Basler, K.,Korkhov, V.M. Cryo-EM structure of the Hedgehog release protein Dispatched. Sci Adv, 6:eaay7928-eaay7928, 2020 Cited by PubMed: 32494603 DOI: 10.1126/sciadv.aay7928 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.76 Å)

Structure validation