6TD6
Structure of Drosophila melanogaster Dispatched bound to a modified Hedgehog ligand, HhN-C85II
Summary for 6TD6
Entry DOI | 10.2210/pdb6td6/pdb |
EMDB information | 10452 10464 |
Descriptor | Protein dispatched, Protein hedgehog, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | rnd transporter, dispatched, hedgehog, transmembrane domain, ectodomain, cholesteryl hemisuccinate, detergent micelle, digitonin, monomer, membrane protein |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 2 |
Total formula weight | 192012.61 |
Authors | Korkhov, V.M.,Cannac, F. (deposition date: 2019-11-07, release date: 2020-06-03, Last modification date: 2020-07-29) |
Primary citation | Cannac, F.,Qi, C.,Falschlunger, J.,Hausmann, G.,Basler, K.,Korkhov, V.M. Cryo-EM structure of the Hedgehog release protein Dispatched. Sci Adv, 6:eaay7928-eaay7928, 2020 Cited by PubMed: 32494603DOI: 10.1126/sciadv.aay7928 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.76 Å) |
Structure validation
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