6TAJ

Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase in complex with Orotic acid 1.60 Angstrom resolution

This is a non-PDB format compatible entry.

Summary for 6TAJ

• Entry DOI: 10.2210/pdb6taj/pdb
• Descriptor: Orotate phosphoribosyltransferase, OROTIC ACID, GLYCEROL, ... (4 entities in total)
• Functional Keywords: orotate phosphoribosyltransferase (oprt), orotic acid, transferase
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 47686.31

Authors

Navas-Yuste, S.,Lopez-Estepa, M.,Gomez, S.,Fernandez, F.J.,Vega, M.C. (deposition date: 2019-10-29, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Roca, M.,Navas-Yuste, S.,Zinovjev, K.,Lopez-Estepa, M.,Gomez, S.,Fernandez, F.J.,Vega, M.C.,Tunon, I.; Elucidating the Catalytic Reaction Mechanism of Orotate Phosphoribosyltransferase by Means of X-ray Crystallography and Computational Simulations; Acs Catalysis, 10:1871-1885, 2020; DOI: 10.1021/acscatal.9b05294

Experimental method

X-RAY DIFFRACTION (1.6 Å)