6T9N

CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2

6T9N の概要

• エントリーDOI: 10.2210/pdb6t9n/pdb
• EMDBエントリー: 10418
• 分子名称: Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... (6 entities in total)
• 機能のキーワード: ion channel, transient receptor potential channel, polycystic kidney disease, structural genomics, structural genomics consortium, sgc, membrane protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 276891.48

構造登録者

Wang, Q.,Pike, A.C.W.,Grieben, M.,Baronina, A.,Nasrallah, C.,Shintre, C.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (登録日: 2019-10-28, 公開日: 2019-11-20, 最終更新日: 2020-07-29)

• 主引用文献: Wang, Q.,Corey, R.A.,Hedger, G.,Aryal, P.,Grieben, M.,Nasrallah, C.,Baronina, A.,Pike, A.C.W.,Shi, J.,Carpenter, E.P.,Sansom, M.S.P.; Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.; Structure, 28:169-184.e5, 2020; PubMed: 31806353; DOI: 10.1016/j.str.2019.11.005

実験手法

ELECTRON MICROSCOPY (2.96 Å)