6T7Z

KEAP1 IN COMPLEX WITH COMPOUND 44

6T7Z の概要

• エントリーDOI: 10.2210/pdb6t7z/pdb
• 分子名称: Kelch-like ECH-associated protein 1, ACE-CYS-ASA-4FB-GLU-THR-GLY-GLU-CYS-NH2, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: keap1, ubiquitinylation, inrf2, kiaa0132, klhl19, proteros biostructures gmbh, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33082.87

構造登録者

Colarusso, S. (登録日: 2019-10-23, 公開日: 2020-09-09, 最終更新日: 2024-06-26)

• 主引用文献: Colarusso, S.,De Simone, D.,Frattarelli, T.,Andreini, M.,Cerretani, M.,Missineo, A.,Moretti, D.,Tambone, S.,Kempf, G.,Augustin, M.,Steinbacher, S.,Munoz-Sanjuan, I.,Park, L.,Summa, V.,Tomei, L.,Bresciani, A.,Dominguez, C.,Toledo-Sherman, L.,Bianchi, E.; Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction.; Bioorg.Med.Chem., 28:115738-115738, 2020; PubMed: 33065433; DOI: 10.1016/j.bmc.2020.115738

実験手法

X-RAY DIFFRACTION (2 Å)