6T7V

KEAP1 IN COMPLEX WITH PEPTIDE 8

Summary for 6T7V

• Entry DOI: 10.2210/pdb6t7v/pdb
• Descriptor: Kelch-like ECH-associated protein 1, LEU-ASP-PRO-GLU-THR-GLY-GLU-PHE-LEU, ACETATE ION, ... (4 entities in total)
• Functional Keywords: keap1, ubiquitinylation, inrf2, kiaa0132, klhl19, proteros biostructures gmbh, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 33030.91

Authors

Colarusso, S. (deposition date: 2019-10-23, release date: 2020-09-09, Last modification date: 2020-10-28)

• Primary citation: Colarusso, S.,De Simone, D.,Frattarelli, T.,Andreini, M.,Cerretani, M.,Missineo, A.,Moretti, D.,Tambone, S.,Kempf, G.,Augustin, M.,Steinbacher, S.,Munoz-Sanjuan, I.,Park, L.,Summa, V.,Tomei, L.,Bresciani, A.,Dominguez, C.,Toledo-Sherman, L.,Bianchi, E.; Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction.; Bioorg.Med.Chem., 28:115738-115738, 2020; PubMed: 33065433; DOI: 10.1016/j.bmc.2020.115738

Experimental method

X-RAY DIFFRACTION (2.6 Å)