6T33

The unusual structure of Ruminococcin C1 antimicrobial peptide confers activity against clinical pathogens

Summary for 6T33

• Entry DOI: 10.2210/pdb6t33/pdb
• NMR Information: BMRB: 50027
• Descriptor: Ruminococcin C (1 entity in total)
• Functional Keywords: bacteriocin, ruminoccin, antibiotic, thioether bridge, antimicrobial protein
• Biological source: [Ruminococcus] gnavus E1
• Total number of polymer chains: 1
• Total formula weight: 4333.76

Authors

Chiumento, S.,Roblin, C.,Bornet, O.,Nouailler, M.,Muller, C.,Basset, C.,Kieffer-Jaquinod, S.,Coute, Y.,Torelli, S.,Le Pape, L.,Shunemann, V.,Jeannot, K.,Nicoletti, C.,Iranzo, O.,Maresca, M.,Giardina, T.,Fons, M.,Devillard, E.,Perrier, J.,Atta, M.,Guerlesquin, F.,Lafond, M.,Duarte, V. (deposition date: 2019-10-10, release date: 2020-08-12, Last modification date: 2024-06-19)

• Primary citation: Roblin, C.,Chiumento, S.,Bornet, O.,Nouailler, M.,Muller, C.S.,Jeannot, K.,Basset, C.,Kieffer-Jaquinod, S.,Coute, Y.,Torelli, S.,Le Pape, L.,Schunemann, V.,Olleik, H.,De La Villeon, B.,Sockeel, P.,Di Pasquale, E.,Nicoletti, C.,Vidal, N.,Poljak, L.,Iranzo, O.,Giardina, T.,Fons, M.,Devillard, E.,Polard, P.,Maresca, M.,Perrier, J.,Atta, M.,Guerlesquin, F.,Lafond, M.,Duarte, V.; The unusual structure of Ruminococcin C1 antimicrobial peptide confers clinical properties.; Proc.Natl.Acad.Sci.USA, 117:19168-19177, 2020; PubMed: 32719135; DOI: 10.1073/pnas.2004045117

Experimental method

SOLUTION NMR