6SZY
Crystal structure of YTHDC1 with fragment 12 (DHU_DC1_150)
Summary for 6SZY
Entry DOI | 10.2210/pdb6szy/pdb |
Descriptor | YTHDC1, SULFATE ION, 4-propan-2-yl-5,6,7,8-tetrahydro-4~{a}~{H}-quinazolin-2-one, ... (4 entities in total) |
Functional Keywords | fragment, complex, ythdc1, epitranscriptomic, rna binding protein |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 42606.89 |
Authors | Bedi, R.K.,Huang, D.,Sledz, P.,Caflisch, A. (deposition date: 2019-10-02, release date: 2020-03-04, Last modification date: 2024-01-24) |
Primary citation | Bedi, R.K.,Huang, D.,Wiedmer, L.,Li, Y.,Dolbois, A.,Wojdyla, J.A.,Sharpe, M.E.,Caflisch, A.,Sledz, P. Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15:618-625, 2020 Cited by PubMed: 32101404DOI: 10.1021/acschembio.9b00894 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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