6SZG

Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GR839 and GSK513

6SZG の概要

• エントリーDOI: 10.2210/pdb6szg/pdb
• 分子名称: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), 4,5,6,7-tetrahydro-2~{H}-indazole-3-carboxylic acid, (4-chlorophenyl)-[(3~{S})-3-oxidanylpiperidin-1-yl]methanone, ... (5 entities in total)
• 機能のキーワード: inhibitor complex, transferase
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62255.70

構造登録者

Thorpe, J.H. (登録日: 2019-10-02, 公開日: 2020-01-22, 最終更新日: 2024-01-24)

• 主引用文献: Thorpe, J.H.,Wall, I.D.,Sinnamon, R.H.,Taylor, A.N.,Stavenger, R.A.; Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii.; Acta Crystallogr.,Sect.F, 76:40-46, 2020; PubMed: 31929185; DOI: 10.1107/S2053230X19017199

実験手法

X-RAY DIFFRACTION (1.84 Å)