6SY1

Crystal structure of the human 2-oxoadipate dehydrogenase DHTKD1 (E1)

Summary for 6SY1

Entry DOI	10.2210/pdb6sy1/pdb
Descriptor	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	dehydrogenase, transketolase, thiamine pyrophosphate, mg, structural genomics, structural genomics consortium, sgc
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	202775.75
Authors	Bezerra, G.A.,Foster, W.,Shrestha, L.,Pena, I.A.,Coker, J.,Kolker, S.,Nicola, B.B.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Bountra, C.,Yue, W.W.,Structural Genomics Consortium (SGC) (deposition date: 2019-09-26, release date: 2020-06-24, Last modification date: 2024-01-24)
Primary citation	Bezerra, G.A.,Foster, W.R.,Bailey, H.J.,Hicks, K.G.,Sauer, S.W.,Dimitrov, B.,McCorvie, T.J.,Okun, J.G.,Rutter, J.,Kolker, S.,Yue, W.W. Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism. Iucrj, 7:693-706, 2020 Cited by PubMed: 32695416 DOI: 10.1107/S205225252000696X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation