6SY1

Crystal structure of the human 2-oxoadipate dehydrogenase DHTKD1 (E1)

6SY1 の概要

• エントリーDOI: 10.2210/pdb6sy1/pdb
• 分子名称: Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: dehydrogenase, transketolase, thiamine pyrophosphate, mg, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 202775.75

構造登録者

Bezerra, G.A.,Foster, W.,Shrestha, L.,Pena, I.A.,Coker, J.,Kolker, S.,Nicola, B.B.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Bountra, C.,Yue, W.W.,Structural Genomics Consortium (SGC) (登録日: 2019-09-26, 公開日: 2020-06-24, 最終更新日: 2024-01-24)

• 主引用文献: Bezerra, G.A.,Foster, W.R.,Bailey, H.J.,Hicks, K.G.,Sauer, S.W.,Dimitrov, B.,McCorvie, T.J.,Okun, J.G.,Rutter, J.,Kolker, S.,Yue, W.W.; Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism.; Iucrj, 7:693-706, 2020; PubMed: 32695416; DOI: 10.1107/S205225252000696X

実験手法

X-RAY DIFFRACTION (1.87 Å)