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6SXB

XPF-ERCC1 Cryo-EM Structure, DNA-Bound form

Summary for 6SXB
Entry DOI10.2210/pdb6sxb/pdb
EMDB information10338
DescriptorDNA repair endonuclease XPF, DNA excision repair protein ERCC-1, DNA (5'-D(P*CP*AP*GP*AP*TP*GP*CP*TP*GP*A)-3'), ... (4 entities in total)
Functional Keywordsdna repair enzyme. nucleotide excision repair, dna binding protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight143323.48
Authors
Jones, M.L.,Briggs, D.C.,McDonald, N.Q. (deposition date: 2019-09-25, release date: 2020-03-11)
Primary citationJones, M.,Beuron, F.,Borg, A.,Nans, A.,Earl, C.P.,Briggs, D.C.,Snijders, A.P.,Bowles, M.,Morris, E.P.,Linch, M.,McDonald, N.Q.
Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation.
Nat Commun, 11:1120-1120, 2020
Cited by
PubMed: 32111838
DOI: 10.1038/s41467-020-14856-2
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (7.9 Å)
Structure validation

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