6SW5
Crystal structure of the human S-adenosylmethionine synthetase 1 (ligand-free form)
Summary for 6SW5
| Entry DOI | 10.2210/pdb6sw5/pdb |
| Descriptor | S-adenosylmethionine synthase isoform type-1, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | s-adenosylmethionine synthesis, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 175772.46 |
| Authors | Panmanee, J.,Antoyuk, S.V.,Hasnain, S.S. (deposition date: 2019-09-19, release date: 2020-06-17, Last modification date: 2024-01-24) |
| Primary citation | Panmanee, J.,Antonyuk, S.V.,Hasnain, S.S. Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene. Acta Crystallogr D Struct Biol, 76:594-607, 2020 Cited by PubMed: 32496220DOI: 10.1107/S2059798320006002 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report
