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6SW5

Crystal structure of the human S-adenosylmethionine synthetase 1 (ligand-free form)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
S-adenosylmethionine synthase isoform type-1polymer39543703.94UniProt (Q00266)
Pfam (PF00438)
Pfam (PF02772)
Pfam (PF02773)
Homo sapiens (Human)AdoMet synthase 1,Methionine adenosyltransferase 1,MAT 1,Methionine adenosyltransferase I/III,MAT-I/III
2E, L
(A, B)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
3F, G, H, I, J...
(A, B, C, D)
1,2-ETHANEDIOLnon-polymer62.112Chemie (EDO)
4S, T, U, V
(A, B, C, D)
waterwater18.0399Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight174815.4
Non-Polymers*Number of molecules14
Total formula weight957.1
All*Total formula weight175772.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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