6SUA
Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain
Summary for 6SUA
Entry DOI | 10.2210/pdb6sua/pdb |
Descriptor | Neutrophil gelatinase-associated lipocalin, 4F2 cell-surface antigen heavy chain, SULFATE ION, ... (4 entities in total) |
Functional Keywords | lipocalin, lcn2, anticalin, lipocalin-based binding protein, cd98hc, 4f2hc, amino acid transport, presentation of cd98 light chain, interaction with integrin beta subunit, single-pass type ii membrane protein, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 140810.40 |
Authors | Schiefner, A.,Deuschle, F.-C.,Skerra, A. (deposition date: 2019-09-13, release date: 2020-06-17, Last modification date: 2024-01-24) |
Primary citation | Deuschle, F.C.,Schiefner, A.,Brandt, C.,Skerra, A. Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice. Protein Sci., 29:1774-1783, 2020 Cited by PubMed: 32463547DOI: 10.1002/pro.3894 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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