6SUA

Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain

6SUA の概要

• エントリーDOI: 10.2210/pdb6sua/pdb
• 分子名称: Neutrophil gelatinase-associated lipocalin, 4F2 cell-surface antigen heavy chain, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: lipocalin, lcn2, anticalin, lipocalin-based binding protein, cd98hc, 4f2hc, amino acid transport, presentation of cd98 light chain, interaction with integrin beta subunit, single-pass type ii membrane protein, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 140810.40

構造登録者

Schiefner, A.,Deuschle, F.-C.,Skerra, A. (登録日: 2019-09-13, 公開日: 2020-06-17, 最終更新日: 2024-01-24)

• 主引用文献: Deuschle, F.C.,Schiefner, A.,Brandt, C.,Skerra, A.; Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.; Protein Sci., 29:1774-1783, 2020; PubMed: 32463547; DOI: 10.1002/pro.3894

実験手法

X-RAY DIFFRACTION (2.75 Å)