6SSU
Crystal structure of Human Microsomal Glutathione S-Transferase 2 in complex with co-substrate Glutathione
Summary for 6SSU
Entry DOI | 10.2210/pdb6ssu/pdb |
Descriptor | Microsomal glutathione S-transferase 2, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLUTATHIONE, ... (5 entities in total) |
Functional Keywords | er membrane protein, glutathione transferase, mapeg, mgst2, integral membrane enzyme, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 53785.96 |
Authors | Thulasingam, M.,Haeggstrom, J.Z. (deposition date: 2019-09-09, release date: 2021-02-03, Last modification date: 2024-01-24) |
Primary citation | Thulasingam, M.,Orellana, L.,Nji, E.,Ahmad, S.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. Crystal structures of human MGST2 reveal synchronized conformational changes regulating catalysis. Nat Commun, 12:1728-1728, 2021 Cited by PubMed: 33741927DOI: 10.1038/s41467-021-21924-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.499 Å) |
Structure validation
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