6SSB

syk in complex with compound 30

Summary for 6SSB

• Entry DOI: 10.2210/pdb6ssb/pdb
• Descriptor: Tyrosine-protein kinase SYK, ~{N}-[4-[5-[(dimethylamino)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-yl]-3-methyl-1-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,5-a]pyridin-7-amine (3 entities in total)
• Functional Keywords: syk kinase transferase inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 35325.46

Authors

Read, J.A. (deposition date: 2019-09-06, release date: 2020-09-30)

• Primary citation: Read, J.A.; Discovery of a Series of Potent, Selective and Orally Bioavailable SYK Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)