6SQP
Crystal structure of Cat MDM2-S429E RING domain homodimer
Summary for 6SQP
Entry DOI | 10.2210/pdb6sqp/pdb |
Descriptor | E3 ubiquitin-protein ligase Mdm2, ZINC ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | mdm2, mdmx, ubiquitin ligase, e3, phosphorylation, ligase |
Biological source | Felis catus (Cat) More |
Total number of polymer chains | 4 |
Total formula weight | 30628.46 |
Authors | Magnussen, H.M.,Ahmed, S.F.,Huang, D.T. (deposition date: 2019-09-04, release date: 2020-05-06, Last modification date: 2024-01-24) |
Primary citation | Magnussen, H.M.,Ahmed, S.F.,Sibbet, G.J.,Hristova, V.A.,Nomura, K.,Hock, A.K.,Archibald, L.J.,Jamieson, A.G.,Fushman, D.,Vousden, K.H.,Weissman, A.M.,Huang, D.T. Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11:2094-2094, 2020 Cited by PubMed: 32350255DOI: 10.1038/s41467-020-15783-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.21 Å) |
Structure validation
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