6SQC

Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076

6SQC の概要

• エントリーDOI: 10.2210/pdb6sqc/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein, Nuclear receptor coactivator 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: complex, unnatural amino acid, protein binding
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51957.33

構造登録者

Bauer, V.,Schmidtgall, B.,Gogl, G.,Dolenc, j.,Osz, J.,Kostmann, C.,Mitschler, A.,Cousido-Siah, A.,Rochel, N.,Trave, G.,Kieffer, B.,Torbeev, V. (登録日: 2019-09-03, 公開日: 2020-09-30, 最終更新日: 2024-01-31)

• 主引用文献: Bauer, V.,Schmidtgall, B.,Gogl, G.,Dolenc, J.,Osz, J.,Nomine, Y.,Kostmann, C.,Cousido-Siah, A.,Mitschler, A.,Rochel, N.,Trave, G.,Kieffer, B.,Torbeev, V.; Conformational editing of intrinsically disordered protein by alpha-methylation.; Chem Sci, 12:1080-1089, 2020; PubMed: 34163874; DOI: 10.1039/d0sc04482b

実験手法

X-RAY DIFFRACTION (2.28 Å)