6SQ1

Crystal structure of cAMP-dependent Protein Kinase A (CHO PKA) in complex with Aminofasudil

6SQ1 の概要

• エントリーDOI: 10.2210/pdb6sq1/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine, ... (5 entities in total)
• 機能のキーワード: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• 由来する生物種: Cricetulus griseus (Chinese hamster)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41812.76

構造登録者

Oebbeke, M.,Siefker, C.,Heine, A.,Klebe, G. (登録日: 2019-09-03, 公開日: 2020-09-30, 最終更新日: 2024-11-20)

• 主引用文献: Oebbeke, M.,Wienen-Schmidt, B.,Gerber, H.-D.,Heine, A.,Klebe, G.; A crystallographic study of cAMP-dependent Protein Kinase A in complex with different Fasudil-derivatives; To Be Published,

実験手法

X-RAY DIFFRACTION (1.49 Å)