6S9I

Human Brr2 Helicase Region D534C/N1866C in complex with C-tail deleted Jab1

6S9I の概要

• エントリーDOI: 10.2210/pdb6s9i/pdb
• 分子名称: U5 small nuclear ribonucleoprotein 200 kDa helicase, Pre-mRNA-processing-splicing factor 8 (3 entities in total)
• 機能のキーワード: rnp remodeling, pre-mrna splicing, spliceosome catalytic activation, dexd/h-box rna helicase, rna and atp binding, nucleus, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 229776.96

構造登録者

Vester, K.,Santos, K.F.,Wahl, M.C. (登録日: 2019-07-13, 公開日: 2020-01-22, 最終更新日: 2020-02-26)

• 主引用文献: Vester, K.,Santos, K.F.,Kuropka, B.,Weise, C.,Wahl, M.C.; The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.; J.Biol.Chem., 295:2097-2112, 2020; PubMed: 31914407; DOI: 10.1074/jbc.RA119.010964

実験手法

X-RAY DIFFRACTION (2.598 Å)