6S8Y

Crystal structure of cytochrome c in complex with a sulfonated quinoline-derived foldamer

6S8Y の概要

• エントリーDOI: 10.2210/pdb6s8y/pdb
• 分子名称: Cytochrome c iso-1, HEME C, ZINC ION, ... (6 entities in total)
• 機能のキーワード: charge interactions, cytochrome c, protein assembly, protein recognition, quinoline foldamer, oxidoreductase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17011.18

構造登録者

Alex, J.M.,Corvaglia, V.,Hu, X.,Engilberge, S.,Huc, I.,Crowley, P.B. (登録日: 2019-07-10, 公開日: 2019-09-25, 最終更新日: 2024-10-16)

主引用文献

Alex, J.M.,Corvaglia, V.,Hu, X.,Engilberge, S.,Huc, I.,Crowley, P.B.
Crystal structure of a protein-aromatic foldamer composite: macromolecular chiral resolution.
Chem.Commun.(Camb.), 55:11087-11090, 2019

PubMed Abstract: Co-crystallization of a 2 kDa tether-free sulfonated foldamer and the 13 kDa lysine-rich cytochrome c yielded a remarkable biohybrid assembly with chiral resolution of the foldamer helix handedness. In the crystal a ∼5 nm foldamer stack was surrounded by eight molecules of protein. NMR and CD experiments suggest interesting differences in the solution state recognition processes.

PubMed: 31460523
DOI: 10.1039/c9cc05330a

実験手法

X-RAY DIFFRACTION (2.09 Å)