6S8L

Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes

6S8L の概要

• エントリーDOI: 10.2210/pdb6s8l/pdb
• 分子名称: Tubulin alpha-1B chain, Tubulin beta-3 chain, Designed ankyrin repeat protein (DARPIN) D1, ... (8 entities in total)
• 機能のキーワード: tubulin, microtubules, microtubule targeting agents, cancer, structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 118700.25

構造登録者

Sharma, A.,Olieric, N.,Steinmetz, M. (登録日: 2019-07-10, 公開日: 2019-11-27, 最終更新日: 2024-05-15)

• 主引用文献: La Sala, G.,Olieric, N.; Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes; Chem, 2019; DOI: 10.1016/j.chempr.2019.08.022

実験手法

X-RAY DIFFRACTION (1.801 Å)