6S6D

Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex

Summary for 6S6D

• Entry DOI: 10.2210/pdb6s6d/pdb
• Descriptor: Ras-related GTP-binding protein A, Ras-related GTP-binding protein C, GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: small gtpases, mtorc1 activator, roadblock domain, gtpase domain, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 163987.78

Authors

Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Kaufman, J.,Williams, R.L. (deposition date: 2019-07-02, release date: 2019-10-16, Last modification date: 2024-05-15)

• Primary citation: Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Berndt, A.,Kaufman, J.,Johnson, C.M.,Santhanam, B.,Rogala, K.B.,Sabatini, D.M.,Williams, R.L.; Architecture of human Rag GTPase heterodimers and their complex with mTORC1.; Science, 366:203-210, 2019; PubMed: 31601764; DOI: 10.1126/science.aax3939

Experimental method

X-RAY DIFFRACTION (2.5 Å)