6S3Q
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with TFB-TBOA
Summary for 6S3Q
Entry DOI | 10.2210/pdb6s3q/pdb |
EMDB information | 10094 |
Descriptor | Excitatory amino acid transporter 3, (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total) |
Functional Keywords | glutamate, aspartate transporter, cysteine, inhibitor complex, membrane protein, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 174349.98 |
Authors | Baronina, A.,Pike, A.C.W.,Yu, X.,Dong, Y.Y.,Shintre, C.A.,Tessitore, A.,Chu, A.,Rotty, B.,Venkaya, S.,Mukhopadhyay, S.,Borkowska, O.,Chalk, R.,Shrestha, L.,Burgess-Brown, N.A.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Han, S.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-25, release date: 2020-07-08, Last modification date: 2024-05-22) |
Primary citation | Baronina, A.,Pike, A.C.W.,Han, S.,Carpenter, E.P. Structure of human excitatory amino acid transporter 3 (EAAT3) TO BE PUBLISHED, |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
Download full validation report