6S0E

Crystal structure of an inverting family GH156 exosialidase from uncultured bacterium pG7 in complex with N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid

Summary for 6S0E

Entry DOI	10.2210/pdb6s0e/pdb
Descriptor	exosialidase from uncultured bacterium pG7, GLYCEROL, ACETATE ION, ... (7 entities in total)
Functional Keywords	(beta/alpha )8 barrel, hydrolase, sialidase, inverting, homodimer
Biological source	uncultured bacterium pG7
Total number of polymer chains	2
Total formula weight	119534.18
Authors	Bule, P.,Blagova, E.,Chuzel, L.,Taron, C.H.,Davies, G.J. (deposition date: 2019-06-14, release date: 2019-11-06, Last modification date: 2024-01-24)
Primary citation	Bule, P.,Chuzel, L.,Blagova, E.,Wu, L.,Gray, M.A.,Henrissat, B.,Rapp, E.,Bertozzi, C.R.,Taron, C.H.,Davies, G.J. Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action. Nat Commun, 10:4816-4816, 2019 Cited by PubMed: 31645552 DOI: 10.1038/s41467-019-12684-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation