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6RZM

Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:5(Iodine)

Summary for 6RZM
Entry DOI10.2210/pdb6rzm/pdb
DescriptorGalectin-3, (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(3-iodanylphenyl)sulfanyl-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordslectin, carbohydrate-binding protein, galactose-specific lectin 3, galactoside-binding protein, galbp, ige-6 binding protein, l-31, laminin-binding protein, lectin l-29, mac-2, sugar binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight16421.95
Authors
Kumar, R.,Verteramo, M.L.,Nilsson, U.J.,Logan, D.T. (deposition date: 2019-06-13, release date: 2020-07-08, Last modification date: 2024-01-24)
Primary citationVerteramo, M.L.,Zetterberg, F.,Kumar, R.,Wallerstein, J.,Ignjatovic, M.M.,Leffler, H.,Ryde, U.,Logan, D.T.,Akke, M.,Nilsson, U.J.
Thermodynamic studies of halogen-bond interactions in galectin-3
to be published,
Experimental method
X-RAY DIFFRACTION (1.345 Å)
Structure validation

218500

PDB entries from 2024-04-17

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