6RV2
Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation
Summary for 6RV2
Entry DOI | 10.2210/pdb6rv2/pdb |
Descriptor | Potassium channel subfamily K member 3, POTASSIUM ION, CHOLESTEROL HEMISUCCINATE, ... (6 entities in total) |
Functional Keywords | membrane protein, potassium channel, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 128796.19 |
Authors | Rodstrom, K.E.J.,Pike, A.C.W.,Zhang, W.,Quigley, A.,Speedman, D.,Mukhopadhyay, S.M.M.,Shrestha, L.,Chalk, R.,Venkaya, S.,Bushell, S.R.,Tessitore, A.,Burgess-Brown, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2019-05-30, release date: 2019-08-07, Last modification date: 2024-01-24) |
Primary citation | Rodstrom, K.E.J.,Kiper, A.K.,Zhang, W.,Rinne, S.,Pike, A.C.W.,Goldstein, M.,Conrad, L.J.,Delbeck, M.,Hahn, M.G.,Meier, H.,Platzk, M.,Quigley, A.,Speedman, D.,Shrestha, L.,Mukhopadhyay, S.M.M.,Burgess-Brown, N.A.,Tucker, S.J.,Muller, T.,Decher, N.,Carpenter, E.P. A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582:443-447, 2020 Cited by PubMed: 32499642DOI: 10.1038/s41586-020-2250-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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