6RUU
Pseudokinase domain of human IRAK3
Summary for 6RUU
Entry DOI | 10.2210/pdb6ruu/pdb |
Descriptor | Interleukin-1 receptor-associated kinase 3, MERCURY (II) ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | pseudokinase, homo-dimer, innate immunity, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 111178.09 |
Authors | Lange, S.M.,Kulathu, Y.,Cohen, P. (deposition date: 2019-05-29, release date: 2020-09-09, Last modification date: 2024-01-24) |
Primary citation | Lange, S.M.,Nelen, M.I.,Cohen, P.,Kulathu, Y. Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation. Structure, 29:238-, 2021 Cited by PubMed: 33238146DOI: 10.1016/j.str.2020.11.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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