6RUP

Human mitochondrial single-stranded DNA binding protein, SSBP1, at 2.1 A resolution - elucidated sequence

Summary for 6RUP

• Entry DOI: 10.2210/pdb6rup/pdb
• Descriptor: Single-stranded DNA-binding protein, mitochondrial, SER-SER-SER-SER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: single-stranded dna binding protein, mitochondria, mtdna, mtdna replication, mitochondrial rna granules, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 33394.05

Authors

Tarres-Sole, A.,Chakraborty, A.,Spelbrink, H.N.,Delettre, C.,Sola, M. (deposition date: 2019-05-28, release date: 2019-10-09, Last modification date: 2024-01-24)

• Primary citation: Piro-Megy, C.,Sarzi, E.,Tarres-Sole, A.,Pequignot, M.,Hensen, F.,Quiles, M.,Manes, G.,Chakraborty, A.,Senechal, A.,Bocquet, B.,Cazevieille, C.,Roubertie, A.,Muller, A.,Charif, M.,Goudenege, D.,Lenaers, G.,Wilhelm, H.,Kellner, U.,Weisschuh, N.,Wissinger, B.,Zanlonghi, X.,Hamel, C.,Spelbrink, J.N.,Sola, M.,Delettre, C.; Dominant mutations in mtDNA maintenance gene SSBP1 cause optic atrophy and foveopathy.; J.Clin.Invest., 130:143-156, 2020; PubMed: 31550237; DOI: 10.1172/JCI128513

Experimental method

X-RAY DIFFRACTION (2.1 Å)