6RTI

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g

Summary for 6RTI

• Entry DOI: 10.2210/pdb6rti/pdb
• Descriptor: Glutamate carboxypeptidase 2, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... (12 entities in total)
• Functional Keywords: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; aptamer, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 98360.82

Authors

Motlova, L.,Kolenko, P.,Barinka, C. (deposition date: 2019-05-24, release date: 2020-06-10, Last modification date: 2024-01-24)

• Primary citation: Ptacek, J.,Zhang, D.,Qiu, L.,Kruspe, S.,Motlova, L.,Kolenko, P.,Novakova, Z.,Shubham, S.,Havlinova, B.,Baranova, P.,Chen, S.J.,Zou, X.,Giangrande, P.,Barinka, C.; Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.; Nucleic Acids Res., 48:11130-11145, 2020; PubMed: 32525981; DOI: 10.1093/nar/gkaa494

Experimental method

X-RAY DIFFRACTION (2.2 Å)