6RTI

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g

6RTI の概要

• エントリーDOI: 10.2210/pdb6rti/pdb
• 分子名称: Glutamate carboxypeptidase 2, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... (12 entities in total)
• 機能のキーワード: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; aptamer, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98360.82

構造登録者

Motlova, L.,Kolenko, P.,Barinka, C. (登録日: 2019-05-24, 公開日: 2020-06-10, 最終更新日: 2024-01-24)

• 主引用文献: Ptacek, J.,Zhang, D.,Qiu, L.,Kruspe, S.,Motlova, L.,Kolenko, P.,Novakova, Z.,Shubham, S.,Havlinova, B.,Baranova, P.,Chen, S.J.,Zou, X.,Giangrande, P.,Barinka, C.; Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.; Nucleic Acids Res., 48:11130-11145, 2020; PubMed: 32525981; DOI: 10.1093/nar/gkaa494

実験手法

X-RAY DIFFRACTION (2.2 Å)