6RSD
Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class
Summary for 6RSD
Entry DOI | 10.2210/pdb6rsd/pdb |
Related | 6rsb 6rsc |
Descriptor | Tyrosine-protein kinase JAK1, 1-[4-(cyanomethyl)-1-[(3-oxidanyl-4-phenyl-phenyl)methyl]piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide (3 entities in total) |
Functional Keywords | inhibitor, complex, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 70490.34 |
Authors | |
Primary citation | Zak, M.,Gibbons, P.,Brown, D.G. Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class To Be Published, |
Experimental method |
Structure validation
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