6RQK

Crystal structure of GH125 1,6-alpha-mannosidase from Clostridium perfringens in complex with mannoimidazole

Summary for 6RQK

Entry DOI	10.2210/pdb6rqk/pdb
Descriptor	Alpha-1,6-mannosidase, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL (3 entities in total)
Functional Keywords	carbohydrate, inhibitor, glycoside hydrolase, complex, hydrolase
Biological source	Clostridium perfringens str. 13
Total number of polymer chains	2
Total formula weight	102524.75
Authors	Males, A.,Davies, G.J. (deposition date: 2019-05-16, release date: 2019-08-28, Last modification date: 2024-01-24)
Primary citation	Males, A.,Speciale, G.,Williams, S.J.,Davies, G.J. Distortion of mannoimidazole supports a B2,5boat transition state for the family GH125 alpha-1,6-mannosidase from Clostridium perfringens. Org.Biomol.Chem., 17:7863-7869, 2019 Cited by PubMed: 31407758 DOI: 10.1039/c9ob01161g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation