6RL5

The first crystal structure of the DABA aminotransferase EctB in the ectoine biosynthesis pathway of the model organism Chromohalobacter salexigens DSM 3034

Summary for 6RL5

• Entry DOI: 10.2210/pdb6rl5/pdb
• Descriptor: Diaminobutyrate--2-oxoglutarate transaminase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: ectoine, daba aminotransferase, osmoadaptation, transferase
• Biological source: Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
• Total number of polymer chains: 8
• Total formula weight: 378666.14

Authors

Hillier, H.T.,Altermark, B.,Leiros, I. (deposition date: 2019-05-01, release date: 2020-03-11, Last modification date: 2024-01-24)

• Primary citation: Hillier, H.T.,Altermark, B.,Leiros, I.; The crystal structure of the tetrameric DABA-aminotransferase EctB, a rate-limiting enzyme in the ectoine biosynthesis pathway.; Febs J., 287:4641-4658, 2020; PubMed: 32112674; DOI: 10.1111/febs.15265

Experimental method

X-RAY DIFFRACTION (2.45 Å)