6RK9
Aspartyl/Asparaginyl beta-hydroxylase (AspH)oxygenase and TPR domains in complex with manganese, N-oxalylglycine and cyclic peptide substrate mimic of factor X
Replaces: 5JZZSummary for 6RK9
Entry DOI | 10.2210/pdb6rk9/pdb |
Related | 5JQY 5JTC 5JZ6 5JZ8 5JZA 5JZU |
Descriptor | Aspartyl/asparaginyl beta-hydroxylase, ACA-LYS-ASP-GLY-LEU-GLY-GLU-TYR-THR-CYS-THR-SER-LEU-GLU-GLY-PHE-GLU, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | 2-oxoglutarate dependent oxygenase, aspartyl/asparaginyl beta-hydroxylase, egf-like domain hydroxylase, double stranded beta-helix, tetratricopeptide repeat, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 101221.90 |
Authors | McDonough, M.A.,Pfeffer, I. (deposition date: 2019-04-30, release date: 2019-05-08, Last modification date: 2024-01-24) |
Primary citation | Pfeffer, I.,Brewitz, L.,Krojer, T.,Jensen, S.A.,Kochan, G.T.,Kershaw, N.J.,Hewitson, K.S.,McNeill, L.A.,Kramer, H.,Munzel, M.,Hopkinson, R.J.,Oppermann, U.,Handford, P.A.,McDonough, M.A.,Schofield, C.J. Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nat Commun, 10:4910-4910, 2019 Cited by PubMed: 31659163DOI: 10.1038/s41467-019-12711-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.292 Å) |
Structure validation
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