6RJJ
Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide
Summary for 6RJJ
Entry DOI | 10.2210/pdb6rjj/pdb |
Related | 6RIT |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (8 entities in total) |
Functional Keywords | inhibitor, complex, co2 conversion, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31176.40 |
Authors | Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2019-04-27, release date: 2020-04-15, Last modification date: 2024-01-24) |
Primary citation | Glockner, S.,Ngo, K.,Wagner, B.,Heine, A.,Klebe, G. The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10:-, 2020 Cited by PubMed: 32230853DOI: 10.3390/biom10040509 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.056 Å) |
Structure validation
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