6RGA

Crystal structure of NAD kinase 1 from Listeria monocytogenes in complexe with an inhibitor

Summary for 6RGA

Entry DOI	10.2210/pdb6rga/pdb
Descriptor	NAD kinase 1, CITRIC ACID, (2~{R},3~{S},4~{R},5~{R})-2-(aminomethyl)-5-[8-[3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy]prop-1-ynyl]-6-azanyl-purin-9-yl]oxolane-3,4-diol, ... (4 entities in total)
Functional Keywords	tetrameric nad kinase, transferase
Biological source	Listeria monocytogenes EGD-e
Total number of polymer chains	1
Total formula weight	31806.93
Authors	Gelin, M.,Labesse, G. (deposition date: 2019-04-16, release date: 2020-02-19, Last modification date: 2020-03-25)
Primary citation	Gelin, M.,Paoletti, J.,Nahori, M.A.,Huteau, V.,Leseigneur, C.,Jouvion, G.,Dugue, L.,Clement, D.,Pons, J.L.,Assairi, L.,Pochet, S.,Labesse, G.,Dussurget, O. From Substrate to Fragments to Inhibitor ActiveIn VivoagainstStaphylococcus aureus. Acs Infect Dis., 6:422-435, 2020 Cited by PubMed: 32017533 DOI: 10.1021/acsinfecdis.9b00368 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation