6RFQ

Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2

Summary for 6RFQ

• Entry DOI: 10.2210/pdb6rfq/pdb
• EMDB information: 4872
• Descriptor: Subunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I), Subunit NUJM of NADH:Ubiquinone Oxidoreductase (Complex I), Subunit NUKM of NADH:Ubiquinone Oxidoreductase (Complex I), ... (52 entities in total)
• Functional Keywords: complex i, nadh dehydrogenase, mitochondrion proton pumping, ubiquinone, oxidoreductase
• Biological source: Yarrowia lipolytica (Candida lipolytica); More
• Total number of polymer chains: 41
• Total formula weight: 1000929.80

Authors

Parey, K.,Vonck, J. (deposition date: 2019-04-16, release date: 2019-12-11, Last modification date: 2021-06-02)

• Primary citation: Parey, K.,Haapanen, O.,Sharma, V.,Kofeler, H.,Zullig, T.,Prinz, S.,Siegmund, K.,Wittig, I.,Mills, D.J.,Vonck, J.,Kuhlbrandt, W.,Zickermann, V.; High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.; Sci Adv, 5:eaax9484-eaax9484, 2019; PubMed: 31844670; DOI: 10.1126/sciadv.aax9484

Experimental method

ELECTRON MICROSCOPY (3.3 Å)