6RFP

ERK2 MAP kinase with mutations at Helix-G

6RFP の概要

• エントリーDOI: 10.2210/pdb6rfp/pdb
• 分子名称: Mitogen-activated protein kinase 1 (2 entities in total)
• 機能のキーワード: nled, effectors, t3ss, map kinase, phosphorylation, transferase
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43425.74

構造登録者

Livnah, O.,Eitan-Wexler, M. (登録日: 2019-04-16, 公開日: 2020-05-13, 最終更新日: 2024-01-24)

• 主引用文献: Gur-Arie, L.,Eitan-Wexler, M.,Weinberger, N.,Rosenshine, I.,Livnah, O.; The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.; J.Biol.Chem., 295:9409-9420, 2020; PubMed: 32404367; DOI: 10.1074/jbc.RA120.013590

実験手法

X-RAY DIFFRACTION (1.74 Å)