6RCU

PfRH5 bound to monoclonal antibodies R5.004 and R5.016

Summary for 6RCU

Entry DOI	10.2210/pdb6rcu/pdb
Related	6RCO 6RCQ 6RCS
Descriptor	Reticulocyte binding protein homologue 5, R5.004 heavy chain, R5.004 light chain, ... (5 entities in total)
Functional Keywords	plasmodium falciparum erythrocyte invasion potentiating antibody neutralising antibody human monoclonal antibody, cell adhesion
Biological source	Plasmodium falciparum (isolate 3D7) More
Total number of polymer chains	5
Total formula weight	182555.43
Authors	Alanine, D.W.G.,Draper, S.J.,Higgins, M.K. (deposition date: 2019-04-11, release date: 2019-06-26, Last modification date: 2019-08-21)
Primary citation	Alanine, D.G.W.,Quinkert, D.,Kumarasingha, R.,Mehmood, S.,Donnellan, F.R.,Minkah, N.K.,Dadonaite, B.,Diouf, A.,Galaway, F.,Silk, S.E.,Jamwal, A.,Marshall, J.M.,Miura, K.,Foquet, L.,Elias, S.C.,Labbe, G.M.,Douglas, A.D.,Jin, J.,Payne, R.O.,Illingworth, J.J.,Pattinson, D.J.,Pulido, D.,Williams, B.G.,de Jongh, W.A.,Wright, G.J.,Kappe, S.H.I.,Robinson, C.V.,Long, C.A.,Crabb, B.S.,Gilson, P.R.,Higgins, M.K.,Draper, S.J. Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178:216-228.e21, 2019 Cited by PubMed: 31204103 DOI: 10.1016/j.cell.2019.05.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.005 Å)

Structure validation