Summary for 6RAV
| Related | 6QSX 6QSW |
|---|---|
| Descriptor | Complement factor B, SULFATE ION, 4-[(2~{S},4~{S})-4-ethoxy-1-[(5-methoxy-7-methyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, ... (5 entities in total) |
| Functional Keywords | complement, immune, inhibitor, c3 convertase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total molecular weight | 67367.93 |
| Authors | Adams, C.M.,Sellner, H.,Ehara, T.,Mac Sweeney, A.,Crowley, M.,Anderson, K.,Karki, R.,Mainolfi, N.,Valeur, E.,Sirockin, F.,Gerhartz, B.,Erbel, P.,Hughes, N.,Smith, T.M.,Cumin, F.,Argikar, U.,Mogi, M.,Sedrani, R.,Wiesmann, C.,Jaffee, B.,Maibaum, J.,Flohr, S.,Harrison, R.,Eder, J. (deposition date: 2019-04-08, release date: 2019-04-17, Last modification date: 2019-04-24) |
| Primary citation | Adams, C.M.,Eder, J. Complement factor B protease domain in complex with the reversible inhibitor 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid To be published, |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
